Calciphylaxis associated with widespread pulmonary calcification

Calciphylaxis with extensive arterial calcification

Calciphylaxis is a clinical syndrome of arteriolar calcification with resultant tissue necrosis, most commonly seen in patients with end-stage renal disease (ESRD) on dialysis. This condition carries a high mortality rate mainly due to infection. Helpful interventions include adequate dialytic therapy, medical management of hyperparathyroidism, hyperphosphatemia, and intravenous sodium thiosulf...

Calciphylaxis: Temporal Artery Calcification Preceding Widespread Skin Lesions and Penile Necrosis

Temporal artery calciphylaxis has rarely been described in chronic kidney disease patients on dialysis. We report a case of 72-year-old Caucasian man with multiple comorbidities and end-stage renal disease on dialysis who presented with temporal artery calcification leading to bilateral loss of vision followed by extensive skin lesions including one on glans penis. While on peritoneal dialysis,...

Localised pulmonary metastatic calcification associated with pulmonary artery obstruction.

BACKGROUND Metastatic pulmonary calcification, a complication of uraemia and disordered calcium metabolism, may be diffuse or localised. The factors that determine calcium precipitation are complex, but tissue alkalosis is thought to be important. As obstruction of the pulmonary artery theoretically causes local alkalosis a retrospective necropsy study was carried out to examine the relation be...

Perieccrine and pericapillary calcification in calciphylaxis

*Corresponding author: Jeong Hee Cho-Vega, MD, PhD, Department of Pathology, Dermatopathology Division, Miami, USA, Email: [email protected] A 44-year-old Hispanic man presented with painful feet and penis. The past medical history was notable for end-stage renal disease, type 2 diabetes mellitus, hypertension, and peripheral vascular disease. The patient was on peritoneal dialysis. Medicati...

Regression of vascular calcification in a patient with calciphylaxis.